From 2000 to 2020, more than 800,000 people died by suicide in the United States. Males represented 78.7% of all suicides between 2000 and 2020. [2] . In 2022, a record high 49,500 people died by suicide. [7] . The 2022 rate was the highest level since 1941, at 14.3 per 100,000 persons. [8] .