Life begins with a single fertilized cell that gradually transforms into a multicellular organism. This process requires ...
In our February issue, Steven Reiner describes how lymphocytes make use of a highly unusual type of division to create two different kinds of cells: effector and memory. Here, you can see this ...
The curved shape of a zebrafish egg causes unequal cell divisions, creating larger cells near the animal pole and smaller ...
How does the body produce the diversity in T-cell fates that are essential for immunity? The symmetric division model predicts that the fate of each naïve T-cell is determined by the cytokines the ...
T cell division is critical to understand because of its role in the immune response. There is a myriad of T cell subcategories with different responsibilities. A few subcategories include cytotoxic T ...
It's long been assumed that when a parent cell divides into two daughter cells, the parent assumes a spherical shape, which then splits into two cells that have roughly the same, round size. But a new ...
Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...
When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell inherits different cellular components, which drive the cells toward divergent ...
T stem cells normally undergo asymmetric cell division (left) whereby one daughter cell becomes a long-lived memory T cell. When autophagy is disrupted, both daughter cells inherit old mitochondria ...