This paper presents serial cardiac-catheterization data showing spontaneous functional closure of large symptomatic defects in 3 infants. One had an associated moderate-sized patent ductus arteriosus ...

Patients with migraine, patent foramen ovale (PFO), and atrial septal aneurysm (ASA) have more frequent ischemic brain lesions, migraine with aura, and larger PFO sizes than patients with migraines ...

Atrial septal defect is an abnormal hole in the fibrous membrane separating the two smaller, collecting chambers of the heart (atria). There are no clear reasons for the development of septal defects.

Expert Rev Cardiovasc Ther. 2007;5(6):1135-1146. Diagnosing a secundum ASD is more often than not incidental because the defect normally causes symptoms late in adult life. Echocardiography and MRI ...

An atrial septal defect is the persistence of a hole (the foramen ovale) in the wall (septum) between the right atrium and left atrium of the heart. The foramen ovale usually closes spontaneously ...

When expectant parents imagine their baby’s beating heart, few consider the possibility of a structural issue being present from day one. Yet for thousands of families each year, this becomes reality ...

Beijing Zhongke Journal Publising Co. Ltd. Congenital heart defects (CHDs) are the most common birth defects, occurring in approximately 0.9% of live births. Sadly, they are also the leading cause of ...

In humans, septal defects are among the most prevalent congenital heart diseases, but their cellular and molecular origins are not fully understood. We report that transcription factor Tbx5 is present ...

The National Institute for Clinical Excellence is examining endovascular closure of atrial septal defect and will publish guidance on its safety and efficacy to the NHS in England, Wales and Scotland.