Atrioventricular septal defect is a developmental irregularity in which a hole connects two or more chambers in your child’s heart. This hole may connect the top two, the bottom two, or all four ...

Atrioventricular septal defects (AVSD) comprise a spectrum of congenital heart malformations characterised by a deficiency of the atrioventricular septum, often resulting in a common atrioventricular ...

Ventricular septal defect is a hole in the wall between the right and left ventricles of the heart. This abnormality usually develops before birth and is found most often in infants. The ventricles ...

High-degree atrioventricular (AV) block (Mobitz II or complete AV block) was an indication in 117 (65%) patients. Forty-four patients (38%) of the 117 patients had congenital complete AV block, 12 of ...

The largest genetic study of congenital heart defects in individuals with Down syndrome found a connection to rare, large genetic deletions affecting cilia, scientists report. The high risk for ...

March 8, 2011 — Smoking in early pregnancy may raise the risk for certain congenital heart defects (CHD) in infants, according to the results of an analysis from the Baltimore-Washington Infant Study ...

Since 1990, the mortality rate for children born with Down syndrome and a congenital heart defect has more than halved. This has been shown by a study by the University of Gothenburg. However, the ...

A comprehensive review offers a 'state of the science' look at the impact of maternal diabetes, and potential gene-environmental influences in that context, on fetal heart development. Congenital ...

An atrioventricular canal is a congenital heart defect that connects chambers of your child’s heart that shouldn’t be connected. Atrioventricular canals usually require surgical treatment. It usually ...

Down syndrome is the most common chromosomal abnormality in humans, involving a third copy of all or part of chromosome 21. In addition to intellectual disability, individuals with Down syndrome have ...