The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to University of Utah Health scientists. Photo credit: Getty ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made ...

Researchers at TalTech have concluded that a lack of creatine does not cause heart failure, contrary to previous assumptions. However, their surprising discoveries about heart muscle cells could lead ...