Researchers have developed a new class of antibodies that amplify the immune system’s ability to fight cancer. By clustering ...

The scientists demonstrated an absence of Ashwell-Morell receptor ligands on glycoforms of intestinal alkaline phosphatase (IAP) featuring glycan chains with two antennae, known as biantennary. They ...

A group of researchers has identified the cause of a 'short-circuit' in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases and could lead to development ...

High-resolution microscopic images of T cells that have been engineered with TGF-beta SNIPRs (shown in red) as they bind to TGF-beta (shown in green). The SNIPRs activate once the receptors fold into ...

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely ...

Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma Colorectal cancer (CRC) remains a major global health burden, being ...

The FDA approval of denileukin diftitox (Lymphir) marked a significant shift in this paradigm. As a first-in-class immunotoxin, it employs a dual-action mechanism: directly targeting interleukin-2 (IL ...

Cells live in a world of chaos, constantly buffeted by random molecular jolts that can derail even the most carefully tuned ...

Global g-protein coupled receptors (GPCRs) market growth is Driven by Rising drug discovery activities, expanding applications in targeted therapeutics, and increasing prevalence of chronic and ...

Pathogens can create sticky situations. When microbes invade the body to cause an infection, often one of their first lines of attack is to cling ...