T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...
Demonstrates how dual-purpose therapeutic targets may address both hepatocellular carcinoma progression and cellular senescence ...
The Immune Atlas identifies immune signatures in MM, enhancing outcome prediction and guiding personalized therapies by ...
Demonstrates how dual-purpose therapeutic targets may address both hepatocellular carcinoma progression and cellular ...
A new study in Molecular Cell shows that a single DNA damage sensor, ATM, fully controls telomere-driven cell aging and that ...
Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent ...
Cold Spring Harbor Laboratory researchers reveal a groundbreaking approach using CAR T-cell therapy to rejuvenate aging ...
A new meeting report was published in Volume 17, Issue 12 of Aging-US on December 23, 2025, titled "Cellular senescence meets ...