Phase I/II study of PTK787/ZK 222584 (PTK/ZK), a novel, oral angiogenesis inhibitor in combination with FOLFIRI as first-line treatment for patients with metastatic colorectal cancer (CRC) We measured ...
We measured dihydropyrimidine dehydrogenase (DPD) activity in peripheral blood mononuclear cells (PBMC), as well as thymidylate synthase (TS) and DPD activity in tissue, in 209 patients with ...
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