Argatroban could revive the practice of acute anticoagulation for reducing disability after stroke, based on the EASE trial from China. In patients with acute ischemic stroke and early neurological ...

Direct thrombin inhibitors prevent the conversion of fibrinogen into fibrin during the coagulation cascade and ultimately prevent the development of a thrombus. 11 Dabigatran etexilate was the first ...

A novel class of antithrombotic medication, the factor XIa inhibitors, has had a rocky start but is powering through phase III trials, which are now underway. MedPage Today sat down to discuss the ...

Coadministration of dabigatran etexilate with the antiplatelet drug clopidogrel had no effect on dabigratran's anticoagulant activity as measured by ECT, activated partial thromboplastin time (aPTT), ...

Potent new anticoagulants have been discovered in the genetic code responsible for the saliva of blood-sucking ticks. Anticoagulants, also known as blood thinners, help prevent unwanted blood clotting ...

Andexanet alfa (Andexxa; AstraZeneca), compared with usual care, improves hemostasis in patients who have an intracranial bleed while taking a factor Xa inhibitor, according to top-line results of ...

Direct oral anticoagulants (DOACs), such as direct thrombin inhibitors and direct factor Xa inhibitors, are increasingly prescribed in various clinical scenarios for both adult and pediatric patients.