Is a value of 150 or 160 mL/min really accurate when using the Cockcroft and Gault equation to calculate creatinine clearance (CrCl)? The use of the filtration marker creatinine, which is generated by ...

Malnutrition is common among patients with cystic fibrosis (CF), which could affect creatinine-based calculation of glomerular filtration rate (GFR). Beringer and colleagues have investigated whether ...

Credit: Shutterstock Accurate assessment of glomerular filtration rate in patients with cancer is crucial to determine drug eligibility and dosing, while balancing the risks for undertreatment and ...

Incorporating β2-microglobulin and β-trace protein filtration markers may improve GFR estimation in patients with solid tumors. Adding the novel endogenous filtration markers β2-microglobulin and ...

Estimates of glomerular filtration rate (GFR) that are based on serum creatinine are routinely used; however, they are imprecise, potentially leading to the overdiagnosis of chronic kidney disease.

1 Laboratory for Biometry and Exercise Nutrition, Free University of Brussels, Brussels, Belgium 2 Laboratory of Medical Chemistry, University Erasmus Academic Hospital, Free University of Brussels, ...

The use of algorithms that alter patient medical care based on race has fallen under increasing criticism, as race-based medicine has been shown to contribute to healthcare disparities. In response, ...

Carboplatin dosing based on renal function has been shown to result in more reproducible and reliable drug exposures than dosing based on surface area in children (Thomas et al, 2000). This approach ...

PenKid is a kidney function biomarker that correlates with gold standard GFR measurements in stable and acute kidney injury (AKI) patients. Based on penKid, a new formula was developed to estimate the ...