Although currently underutilized, granulocyte colony-stimulating factor prophylaxis as supportive cancer care provides substantial value to society. Aligning utilization with clinical guidelines would ...

One of the major dose-limiting toxicities of cytotoxic chemotherapy for non-Hodgkin's lymphoma (NHL) is myelosuppression and subsequent susceptibility to infection. Haemopoietic colony-stimulating ...

Purpose. The efficacy and safety of granulocyte colony-stimulating factor (G-CSF) in critically ill patients with severe sepsis or septic shock were evaluated. Summary. The medical literature was ...

Severe sepsis from bacterial or viral infections can be life-threatening and even people recovering from severe sepsis may experience long-lasting effects on the immune system, making them more ...

Value-based programs, such as the Oncology Care Model (OCM), seek to improve care for patients undergoing chemotherapy, while reducing total costs. The purpose of this study is to quantify the impact ...

Outcome of patients with Hodgkin's disease failing after primary MOPP-ABVD. Comparison of psychologic outcome in adult survivors of childhood acute lymphoblastic leukemia versus sibling controls: a ...

Lee Schwartzberg, MD, FACP: While colony-stimulating factors like G-CSF [granulocyte colony-stimulating factor] have revolutionized the approach to chemotherapy-induced neutropenia [CIN] and febrile ...

The effects of sargramostim and filgrastim on hematopoietic cells are described. Filgrastim is a lineage-specific colonystimulating factor (CSF), mainly affecting neutrophils. In addition to enhancing ...