Human haploid ESCs exhibited typical colony morphology and expressed classical human ESC markers, including alkaline phosphatase, OCT4, NANOG, SSEA4, SOX2, TRA-1-81 and TRA-1-60 (Figure 1E and ...

The study, titled Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions, was published on October 11 in the journal Cell Stem Cell. The ...

Since the emergence of molecular genetics more than fifty years ago, scientists have tried to isolate haploid mammalian cells, that is, cells with half the number of chromosomes contained in somatic ...

In a paper published on aBIOTECH, the authors developed an efficient haploid identification (HID) system for wheat by seamlessly integrating a two-fluorescent protein-based HID toolbox with a ...

Evolution, Vol. 71, No. 2 (FEBRUARY 2017), pp. 215-226 (12 pages) Many organisms spend a significant portion of their life cycle as haploids and as diploids (a haploid–diploid life cycle). However, ...

“In diploid cells, mutating just one copy of a gene usually does not produce a biological effect because there is always a second copy that serves [as] a ‘backup,’” study coauthor Ido Sagi of Hebrew ...

Haploid plants, which carry only a single set of chromosomes, are typically sterile, making them valuable but difficult to use in breeding. A rare peach haploid mutant, '9-D', surprisingly exhibited ...

A common strategy to create high-yielding plants is hybrid breeding. However, getting the inbred lines in the first place can be a hassle. In maize, the use of so-called 'haploid inducers' provides a ...

An agronomist has launched a Doubled Haploid Facility that can develop pure, inbred corn lines in less time than traditional methods. Agronomists at Iowa State University are offering doubled haploid ...

Researchers have created mouse embryonic stem cells that contain only one set of chromosomes, rather than two, according to a study publishing today (September 7) in Nature. The new cells could be ...