Figure 1: DNA repair by homologous recombination. An additional activity noted in studies with Brh2 was its ability to promote a template switch. During DNA replication, homologous recombination is ...

Tokyo, Japan – Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a ...

Homology search is the crucial step during homologous recombination that involves the encounter of two homologous sequences, the constant probing for homology and the final recognition of the ...

Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer This was a prospective, cross-sectional, ...

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...

A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...

Since sister chromatids are identical to each other, recombination with a sister chromatid is expected, in most cases, to be a precise way for repairing DNA damage. Recombination between 2 different ...

In men with metastatic castration-resistant prostate cancer who had disease progression while receiving enzalutamide or abiraterone and who had alterations in genes with a role in homologous ...

New findings suggest an explanation for the century-old mystery of how chromosome recombination is regulated during sexual reproduction. In most higher organisms, including humans, every cell carries ...