“We confirmed that, overall, the presence of endplate lesions was associated with frequent back pain. Particularly, large endplate lesions were associated with both occasional and frequent back pain,” ...

Intervertebral disc (IVD) degeneration and associated back pain place a significant burden on the population. IVD degeneration is a progressive cascade of cellular, compositional and structural ...

Thus, the disk cells themselves can assume the functions of immune cells and can generate alarm signals, triggering the ...

Disc degeneration alone was not found to have much impact on lower back pain; however, researchers found disc degeneration was highly associated with low back pain when combined with endplate signal ...

IN 1948 and 1950 Lindblom 1,2 reported his experience with diskography. In these reports he described a method of direct visualization of normal and pathologic lumbar intervertebral disks by means of ...

Degenerative disc disease is when one or more of the discs between the vertebrae of the spinal column deteriorate or break down, leading to pain. There may be weakness, numbness, and pain that ...

A slipped disk can happen anywhere along the spine. Despite the name, the intervertebral disk does not slip out of place. Instead, the inner material protrudes through the disk’s outer ring, causing ...

Intervertebral disk (ID) degeneration (IDD) is one of the main causes of chronic low back pain, and degenerative lesions are usually caused by an imbalance between catabolic and anabolic processes in ...