The skeleton is among the most commonly injured body tissues. Every year more than 16 million fractures of long bones occur in the United States. Fortunately, bone has excellent regenerative potential ...

Skeletogenesis occurs through either intramembranous or endochondral ossification. In addition, some parts of the skeletal components maintain their cartilaginous characteristics throughout life ...

βig-h3 is a TGF-β-induced extracellular matrix protein which is expressed in many tissues including bones and cartilages. In previous reports, we showed that βig-h3 mediates cell adhesion and ...

"Historically viewed as mainly a “wear and tear” condition, new insights suggest that OA may be part of an evolutionary, age-related biological process rather than mainly driven by mechanical damage." ...