Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Q: My doctor thinks my mast cells are activating inappropriately and may be causing many of the symptoms I periodically have. Please tell me more about this condition. A: Mast cells are an important ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

It's still early science -- studies in mice and in human cells -- but researchers are on the trail of an effective new treatment for inflammatory skin conditions such as rosacea. Skin cells called ...

Allakos is a clinical stage biotechnology company developing therapeutics which target immunomodulatory receptors present on immune effector cells involved in allergy, inflammatory and proliferative ...

PHILADELPHIA, July 31, 2024 /PRNewswire/ -- Mast cells are found throughout the body close to blood vessels and are packed with granules containing the immune signaling compound histamine, and enzymes ...

Third in a series of articles on COVID-19 and its effects on the gut, this article will explore “Long COVID” (also called “post-acute COVID syndrome”) and the role mast cells play in producing gut ...

According to the National Center for Health and Statistics, under the Centers for Disease Control and Prevention (CDC), ...

A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of Pittsburgh study published today in Science Translational Medicine. The ...