The dynamic regulation of chromatin involves four subfamilies of ATP-dependent nucleosome-remodelling complexes: imitation switch (ISWI), chromodomain helicase DNA-binding (CHD), switch/sucrose ...
Despite nearly four decades of clinical experience with Bacillus Calmette–Guérin (BCG) for bladder cancer, the mechanism of its therapeutic effect is still under investigation The requirements for ...
Scientists have known that the cancer drug ONC201 blocks cells from proliferating and kills tumors in cell and animal models—but they haven’t known exactly how it works, or what its molecular target ...
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