Nanoscopy is a field of microscopy that focuses on imaging and studying structures and processes at the nanoscale, typically below the diffraction limit of light. It encompasses various techniques ...

Researchers achieved nanometer-scale resolution without requiring a dark state, expanding super-resolution imaging to non-fluorescent molecules and non-optical waves. The findings published in Nature ...

Genomic deoxyribonucleic acid (DNA) is continuously being damaged by endogenous processes such as metabolism or by exogenous events such as radiation. The specific phosphorylation of histone H2AX on ...

A team has constructed an improved mid-infrared microscope, enabling them to see the structures inside living bacteria at the nanometer scale. Mid-infrared microscopy is typically limited by its low ...

Three-dimensional (3D) super-resolution microscopy is essential to study the minute structural details of cells and analyze molecular dynamics. Recently, researchers at Ludwig-Maximilians-Universität ...

While many researchers use optical nanoscopes for their research, they are currently limited in their resolution due to how light diffracts. While techniques have been developed to combat this, there ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Therapeutic monoclonal antibodies (mAbs) are used in chronic lymphocytic leukemia immunotherapies to target the receptor CD20 at the plasma membrane of immunological B cells. Although they have been ...

Pushing the MINFLUX technique to higher spatial and temporal precision allows protein dynamics to be observed under physiological conditions. Scientists led by Nobel Laureate Stefan Hell at the Max ...

This illustration represents a bacteria being illuminated with mid-infrared in the top left, while visible light from a microscope underneath is used to help capture the image. A team at the ...