Muse Treatment Alcohol & Drug Rehab Los Angeles has published a new educational resource examining how opioid tolerance ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Studies in animal models by UF Scripps Biomedical Research scientists have identified a protein that could shed light on how people develop tolerance to pain-relieving drugs over time, a problem that ...

Opioids are often prescribed for pain management after surgery — but for the 19 million people in the U.S. with a history of substance abuse, that option may not be safe or desired. Until now, there ...

Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...

Jennifer Whistler’s team at the UC Davis Center for Neuroscience is researching ways to make opioid painkillers safer. (Getty Images) Opioids are powerful painkillers but their use is hindered because ...

New research has identified an alternative signaling pathway in the brain of mice that relieves pain, even in animals that have developed tolerance to opioids. The study also showed that pain relief ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

When you have a mild headache or muscle ache, an over-the-counter pain reliever is usually enough to make you feel better. But if your pain is more severe, your doctor might recommend something ...

The FDA has issued new rules related to the prescribing of opioid painkillers. The rules apply to transmucosal immediate-release fentanyl, or TIRF, drugs. The drugs contain fentanyl, a powerful opioid ...

High plasma concentrations of buprenorphine may reduce fentanyl-induced respiratory depression, new research suggests. The primary endpoint measure in a small "proof of principal" pharmacology study ...