Nature

Correction of a short cardiac PR interval in a 12-year-old girl with late-onset Pompe disease following enzyme replacement therapy

To the Editor: We read with interest the article titled “Cardiovascular Abnormalities in Late Onset Pompe Disease and ERT” by Forsha et al. 1. Ninety patients were randomized 2:1 to enzyme replacement ...
Medscape

What's This Repeating Pattern?

The diagnosis is normal sinus rhythm, interpolated premature ventricular complexes (PVCs) in a trigeminal pattern, retrograde concealed conduction, intraventricular conduction delay, and old inferior ...
Nature

Cardiac manifestations of neonatal lupus erythematosus: guidelines to management, integrating clues from the bench and bedside

One of the strongest clinical associations with autoantibodies against components of the SSA/Ro–SSB/La ribonucleoprotein complex is the development of congenital heart block in an offspring, an ...
Medscape

ECG Challenge: Her Annual Physical Is Normal, Except the ECG

The diagnosis is normal sinus rhythm, atrial bigeminy, first-degree atrioventricular (AV) block (prolonged AV conduction), and right bundle branch block (RBBB). The rhythm is slightly irregular, with ...
The New England Journal of Medicine

Therapy of Atrioventricular Block

PROLONGATION of the PR interval beyond 0.20 second may occur in many disorders including acute myocardial infarction, aortic stenosis, severe aortic insufficiency, adrenal insufficiency, rheumatic ...