Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but ...

The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

Baculovirus expression systems have emerged as an indispensable tool in the production of recombinant proteins, offering a robust platform for achieving high-level expression in insect cells. By ...

Membrane proteins are ubiquitous cellular components that are responsible for a wide array of cellular and molecular activities, including drug metabolism, lipid shuttling, and antibiotic resistance.

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

In the past decade there has been significant interest in studying the expression of our genetic code down to the level of single cells, to identify the functions and activities of any cell through ...

Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...