Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries the information contained within DNA to the ribosomes, where the genetic information is synthesized into ...

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

Originally isolated from soil microbes, “anthracyclines rapidly made their way to the clinic and are still one of the most effective compounds we have today,” explained Dr. Matthew Wooten, a ...