How do bacteria — harmless ones living in our bodies, or those that cause disease — organize their activities? A new study, combining powerful genomic-scale microscopy with a technical innovation, ...

Researchers have developed 'tomoseqr' -- a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free to use and has been ...

Spatial transcriptomics is a cutting-edge technique that examines gene expression within tissue sections, such as the heart, skin, or liver. By mapping gene activity in its spatial context, ...

Bacterial gene regulation is a finely tuned process essential for cellular adaptation and survival. Central to this regulation are nucleoid-associated proteins (NAPs), which not only compact the ...

When the Nanog gene (green region) is inactive, one of the three enhancer regions is spatially far away. When active, the same enhancer region makes close contact, interacting with the other enhancers ...

Qiuwen Chen, Yuchen Chen, Jun Yang, Stephen C. Maberly, Jianyun Zhang, Jinren Ni, Gangsheng Wang, Daniele Tonina, Lin Xiao, Honghai Ma https://www.jstor.org/stable ...

Understanding the composition and architecture of cells within tissues is fundamental to studying tissue function and more broadly, human biology. The complex dynamics of cellular functions and ...

In a recent study published in the journal Nature, researchers developed spatial aging clocks using single-cell transcriptomics to explore cell-type-specific interactions and their impact on brain ...