One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.

A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

Genes are segments of DNA (deoxyribonucleic acid) that are located inside every human cell. The DNA inside each cell is tightly coiled in structures called chromosomes. Each chromosome contains a ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

For decades, the Y chromosome – one of the two human sex chromosomes – has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

Researchers identify a novel centromere-specific histone H3 variant called the “CENP-A”, which reconstituted with H4 forms “CENP-A–H4” octasome and explore its role in mitosis. Centromeres, ...

The human Y chromosome, responsible for determining male sex, finally has gotten an end-to-end examination. The Y chromosome is the smallest of the human chromosomes. “In the old time, people thought ...

Pt. A. Gene cloning -- cDNA cloning method using stable expression in mammalian cells / Toru Miki and Stuart A. Aaronson -- Normalization and selection with short-fragment cDNAs / Satish Parimoo, ...

Jenny Graves is a Friend of The Conversation. Neanderthals, the closest cousins of modern humans, lived in parts of Europe and Asia until their extinction some 30,000 years ago. Genetic studies are ...