Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets ...

The field of immunology of ageing is rapidly evolving, with T cells playing a pivotal role in maintaining immune competence and overall organismal ...

New research by scientists at the Champalimaud Foundation has revealed a surprising new role for the immune system. Their study in mice found that during periods of low energy— such as intermittent ...

RRS1, a ribosome-biogenesis factor previously linked to tumor growth, is now shown to be indispensable for normal human ...

Researchers at the Johns Hopkins Kimmel Cancer Center’s Ludwig Center developed a new treatment that selectively targets ...