Combining anthracycline and taxane for early-stage operable breast cancer was more effective than either anthracycline or taxane chemotherapy alone in reducing breast cancer recurrence and death, ...

Patients with early-stage, node-negative, hormone receptor (HR)-positive, HER2- negative breast cancer who have a high risk of recurrence based on the OncotypeDX genomic test had better outcomes when ...

Chromosomal instability, which is a characteristic of many human cancers, contributes to intratumour heterogeneity and has been functionally implicated in resistance to taxane therapy in tumour models ...

Taxanes have become front-line therapy for a variety of metastatic cancers, but resistance can develop, a frequent problem in breast, ovarian, prostate and other cancers. Now, researchers report a ...

Please provide your email address to receive an email when new articles are posted on . Women who use taxane chemotherapy agents may be at a higher risk to develop epiphora, optic neuropathy and ...

Randomized Trial of High-Dose Chemotherapy With Autologous Peripheral-Blood Stem-Cell Support Compared With Standard-Dose Chemotherapy in Women With Metastatic Breast Cancer: NCIC MA.16 Studies were ...

Hearing loss and tinnitus are common among cancer survivors who received treatment with taxane- or platinum-based chemotherapy, a new analysis shows. More specifically, researchers found that more ...

Final results of NKTR-102, a topoisomerase I inhibitor-polymer conjugate, in patients (Pts) with pretreated metastatic breast cancer (MBC) demonstrating significant antitumor activity. MEDI-573 as a ...

The power of taxane-based chemotherapy drugs are misunderstood and potentially underestimated, according to researchers. Most physicians and investigators believe that taxane chemotherapy (paclitaxel, ...

Researchers have identified chromosomal instability in circulating tumour cells as a prognostic and predictive biomarker in ...

Evidence-based recommendations on trastuzumab emtansine (Kadcyla) for human epidermal growth factor receptor 2 (HER2)‑positive, unresectable, locally advanced or metastatic breast cancer in adults who ...