Researchers have discovered a biosynthetic pathway that makes amino acids containing terminal alkynes. Because such functional groups are rare in natural products, they provide a handle for chemistry ...

Alkyne dimerization represents a pivotal reaction in organic synthesis whereby two terminal alkynes combine to yield 1,3-enynes – molecules that constitute key building blocks for natural products, ...

Cycloaddition reactions are an efficient strategy for constructing cyclic compounds that are important building blocks for other chemicals. In these processes, π-electrons from different unsaturated ...

A collaborative academic-industry research team in the U.K. has devised a method to convert the terminal triple bond of an alkyne into a diester with the two ester groups at opposite ends of the ...