Scientists at the Icahn School of Medicine at Mount Sinai have developed a novel artificial intelligence tool that not only ...

Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...

Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing. Tumors can carry ...

Occasionally, single-letter misspellings in the genetic code, known as point mutations, occur. Point mutations that alter the resulting protein sequences are called nonsynonymous mutations, while ...

Myeloid leukemias are among the most aggressive blood cancers and have low survival rates. Today, leukemia patients undergo ...

The first 100 bases of many genes show excess mutations, revealing a major genomic weak spot that shapes disease risk and highlights hidden patterns of inherited change.

In autosomal-dominant AD, mutation type influenced amyloid-PET pegged to estimated years before symptom onset. Some mutations came with more striatal amyloid; some with cortical. CSF Aβ42 did not vary ...