In a recent study published in the journal EMBO Reports, researchers discussed and identified the systemic functions and interactions of 52 active cell surface receptor tyrosine kinases (RTKs), ...
Tyrosine kinases are enzymes involved in the transfer of a phosphate group from adenosine triphosphate (ATP) to specific tyrosine residues of proteins within the cell, acting as an “on/off” switch for ...
Safety analysis of targeted therapy in mRCC: Montenegro experience. A phase 1b dose-escalation study of TRC105 (anti-endoglin antibody) in combination with axitinib in patients with metastatic renal ...