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Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...
Dr. Koneru has extensive experience and expertise in the field of drug development with a track record of advancing novel therapeutics from early development through later-stage clinical programs. She ...
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RNA splicing and processing genes emerge as central drivers of aging across tissues
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A ...
This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...
A well-regarded treatment for trauma, cognitive processing therapy, equips clients with tools to thrive beyond mere survival.
In North Dakota, farmers aren’t neighbors — they’re family. When a sudden car crash tragically took the life of a beloved community member, the goodhearted folks of Antler came together to carry out ...
The past few decades have seen a dramatic shift in how human disorders can be treated. Growing knowledge of the molecular dynamics underlying physiological processes and technological advances are ...
As a small business owner, you know that accepting credit cards comes with a cost. Expanding your customer base to cardholders can create massive profits, but it can also swamp you in expensive swipe ...
Organoid Intelligence (OI) represents a groundbreaking convergence of biology and technology, aiming to redefine biocomputing using brain organoids—three-dimensional neural structures derived from ...
Based Detection, Linguistic Biomarkers, Machine Learning, Explainable AI, Cognitive Decline Monitoring Share and Cite: de Filippis, R. and Al Foysal, A. (2025) Early Alzheimer’s Disease Detection from ...
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