Imetelstat sodium works by blocking the activity of an enzyme called telomerase, which is found at high levels in cells that divide rapidly, including cancer cells. Blocking this enzyme keeps …

Mar 18, 2025 · In June 2024, imetelstat (Rytelo™) became the first telomerase inhibitor approved by the U.S Food and Drug Administration (FDA). Imetelstat treats low- to intermediate-risk …

Jul 16, 2024 · Rytelo (imetelstat) is an injectable telomerase inhibitor that may be used to treat adults with low- to intermediate-1 risk myelodysplastic syndromes (MDS) with transfusion …

Imetelstat, sold under the brand name Rytelo, is an anti-cancer medication used for the treatment of myelodysplastic syndromes with transfusion-dependent anemia. [1] Imetelstat is an …

Jun 16, 2024 · Imetelstat can cause liver toxicity, which your oncology care team may monitor for using blood tests called liver function tests. Notify your healthcare provider if you notice …

RYTELO® (imetelstat) is indicated for treatment of adult patients with low- to intermediate-1 risk myelodysplastic syndromes (MDS) with transfusion-dependent anemia.

The injectable oligonucleotide telomerase inhibitor Imetelstat is the first drug of its kind, as it functions by attaching to the telomerase enzyme, preventing telomere binding and blocking its …

Imetelstat Injection What is this medication? IMETELSTAT (im e TEL stat) treats myelodysplastic syndrome (MDS), a type of blood and bone marrow cancer. It works by blocking a protein that …

Imetelstat is FDA approved for the treatment of adult patients with low- to intermediate-1 risk myelodysplastic syndromes (MDS) with transfusion-dependent anemia requiring 4 or more red …

Imetelstat is a first-in-class, small-molecule, 13-mer oligonucleotide telomerase inhibitor. The imetelstat molecule has a sequence complementary to the ribonucleic acid (RNA) component …