3.7K views · 47 reactions | Valproate can be used to treat bipolar disorder, but should no longer be prescribed to anyone that could become pregnant unless a pregnancy prevention programme is in place. Share this video for anyone that might need it, and check the comments section for more information ⬇️⬇️ | Mind | Facebook
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3.7K views · 47 reactions | Valproate can be used to treat bipolar disord…
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8.5K views · 16 reactions | Valproate is an epilepsy drug that can cause what is called Valproate Syndrome in children born to women using the drug. Sky’s Jason Farrell explains.  Link in bio to read more #Valproate #epilepsy #ValproateSyndrome | Sky News | Facebook
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Aazer Nawab on Instagram: "Valproate-related hyperammonemic encephalopathy (VHE) is a serious but reversible complication of valproic acid therapy. A condition where serum ammonia rises due to valproate, leading to altered mental status, even when LFTs are normal and valproate levels may be therapeutic. -Mechanism Valproate: •Inhibits carbamoyl phosphate synthetase-1 (CPS-1) → blocks urea cycle •Causes carnitine deficiency •Produces toxic metabolites such as 4-en-VPA •Leads to accumulation of am
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